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tp53 protein, human
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NextBio Summary
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Genetic Markers
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No genes found
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Pathway Enrichment
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Curated Studies
Most Correlated Studies
TGF-beta/mutant-p53 subjected to shRNA in MDA-MB-231 cell lines with anti-GFP controls
Mammary tumors from 8 different mouse models of human breast cancer
Pancreatic ductal cancer PANC-1 cells with mutant TP53, TP53-knockdown and treated with TNFA
HCT116 cells isogenic for p53 expression upon treatment with actinomycin D and nutlin-3
Response of breast tumors treated with docetaxel-capecitabine (+/- trastuzumab)
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Literature
Most Relevant Literature
Targeting cancer with bispecific antibodies.
Targeted leukaemia therapy: a chemotherapy-free future?
Cancer surveillance for individuals with Li-Fraumeni syndrome.
Comment on "Deleterious Effect of RAS and Evolutionary High-risk TP53 Double Mutation in Colorectal …
Comment on "Deleterious Effect of RAS and Evolutionary High-risk TP53 Double Mutation in Colorectal …
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Clinical Trials
Most Relevant Clinical Trials
Study of SNX-5422 in TP53 Null Cancers
APR-246 & Azacitidine for the Treatment of TP53 Mutant Myelodysplastic Syndromes (MDS)
Phase II, Single-arm Study of AZD1775 Monotherapy in Relapsed Small Cell Lung Cancer Patients With M…
Trial of AZD5363 Plus Paclitaxel /AZD2014 Plus Paclitaxel in Biomarker Negative (PIK3CA/MEK/RAS/TP53…
Study of AZD1775 in Combination With Paclitaxel, in Advanced Gastric Adenocarcinoma Patients Harbori…
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