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QuickView for tp53 protein, human (compound)
Most Correlated Studies
- TGF-beta/mutant-p53 subjected to shRNA in MDA-MB-231 cell lines with anti-GFP controls
- Mammary tumors from 8 different mouse models of human breast cancer
- Pancreatic ductal cancer PANC-1 cells with mutant TP53, TP53-knockdown and treated with TNFA
- HCT116 cells isogenic for p53 expression upon treatment with actinomycin D and nutlin-3
- Response of breast tumors treated with docetaxel-capecitabine (+/- trastuzumab)
Most Relevant Literature
- The BCL-2 family member BOK promotes KRAS-driven lung cancer progression in a p53-dependent manner.
- Cancer-derived C-terminus-extended p53 mutation confers dominant-negative effect on its wild-type co…
- p53 wild-type colorectal cancer cells that express a fetal gene signature are associated with metast…
- Drugging the Master Regulator TP53 in Cancer: Mission Possible?
- A p53/CPEB2 negative feedback loop regulates renal cancer cell proliferation and migration.
Most Relevant Clinical Trials
- Study of SNX-5422 in TP53 Null Cancers
- APR-246 & Azacitidine for the Treatment of TP53 Mutant Myelodysplastic Syndromes (MDS)
- Entrectinib in Combination With ASTX727 for the Treatment of Relapsed/Refractory TP53 Mutated Acute …
- Phase II, Single-arm Study of AZD1775 Monotherapy in Relapsed Small Cell Lung Cancer Patients With M…
- Trial of AZD5363 Plus Paclitaxel /AZD2014 Plus Paclitaxel in Biomarker Negative (PIK3CA/MEK/RAS/TP53…
