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QuickView for tunicamycin (compound)


Genetic Markers

Most Correlated Genes

  1. DDIT3
  2. NUPR1
  3. HSPA5
  4. CRELD2
  5. ATF3
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Pathway Enrichment

Most Correlated Biogroups

  1. FISCHER_DREAM_TARGETS
  2. PUJANA_BRCA1_PCC_NETWORK
  3. KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
  4. PUJANA_CHEK2_PCC_NETWORK
  5. TIEN_INTESTINE_PROBIOTICS_24HR_DN
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Curated Studies

Most Correlated Studies

  1. Neuroblastoma cell line SH-SY5Y treated with thapsigargin, tunicamycin, or atrazine
  2. Lymphoblastoid TK6 cells treated with various histone deacetylase (HDAC) inhibitors
  3. Prostate cancer LNCaP cells with PERK or ATF4 siRNA knockdown treated with tunicamycin
  4. Cardiomyocytes (mature and progenitors) treated with thapsigargin, tunicamycin or halofuginone
  5. Livers with liver specific LRH1 knockout treated with tunicamycin
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Literature

Most Relevant Literature

  1. Structure-Based Insight on the Mechanism of N-Glycosylation Inhibition by Tunicamycin.
  2. Benefits and Pitfalls of a Glycosylation Inhibitor Tunicamycin in the Therapeutic Implication of Can…
  3. Precursor-Directed Biosynthesis and Biological Testing of omega-Alicyclic- and neo-Branched Tunicamy…
  4. Global regulator AdpA directly binds to tunicamycin gene cluster and negatively regulates tunicamyci…
  5. Concise Synthesis of Tunicamycin V and Discovery of a Cytostatic DPAGT1 Inhibitor.
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Clinical Trials

Most Relevant Clinical Trials

  1. Mechanisms of Cell Death in Spinal Muscular Atrophy
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