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QuickView for withaferin a (compound)


Genetic Markers

Most Correlated Genes

  1. HMOX1
  2. TXNIP
  3. XIST
  4. CRIP1
  5. RBP4
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Pathway Enrichment

Most Correlated Biogroups

  1. organic cyclic compound binding
  2. heterocyclic compound binding
  3. organic cyclic compound metabolic process
  4. BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
  5. heterocycle metabolic process
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Curated Studies

Most Correlated Studies

  1. Broad Connectivity Map (CMAP 2.0) compound database
  2. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
  3. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
  4. L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
  5. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature

Most Relevant Literature

  1. Withaferin A for COVID-19: a Network Pharmacology Approach.
  2. A Homodimer of Withaferin A Formed by Base-Promoted Elimination of Acetic Acid from 27-O-Acetylwitha…
  3. Withaferin A: A potential selective glucocorticoid receptor modulator with anti-inflammatory effect.
  4. Computational Identification of BCR-ABL Oncogenic Signaling as a Candidate Target of Withaferin A an…
  5. Adaptogenic activity of withaferin A on human cervical carcinoma cells using high-definition vibrati…
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Clinical Trials

Most Relevant Clinical Trials

  1. Combination Therapy for Recurrent Ovarian Cancer
  2. The Effects of Ashwagandha in Endurance Exercise Performance
  3. PB125, Osteoarthritis, Pain, Mobility, and Energetics
  4. Withania Somnifera: an Immunomodulator and Anti-inflammatory Agent for Schizophrenia
  5. Topical and Oral Regimen for Skin Health
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