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zileuton
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Summary
General Info
Genetic Markers
Most Correlated Genes
CYP1A1
APOA2
ALOX15
LIPC
ABCC3
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Pathway Enrichment
Most Correlated Biogroups
response to organic substance
organic cyclic compound metabolic process
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP
organic cyclic compound binding
cellular aromatic compound metabolic process
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Curated Studies
Most Correlated Studies
Drug Matrix In Vivo Toxicogenomic Study - Rat Liver [Affymetrix]
Drug Matrix In Vivo Toxicogenomic Study - Rat Kidney [Codelink]
Drug Matrix In Vivo Toxicogenomic Study - Rat Liver [Codelink]
Drug target sets for approved compounds
Liver Pharmacology and Xenobiotic Response Repertoire
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Literature
Most Relevant Literature
Zileuton Ameliorates Neuronal Ferroptosis and Functional Recovery After Spinal Cord Injury.
Evaluation of mucosal immune profile associated with Zileuton nanocrystal-formulated BCS-II drug upo…
Treatment with the 5-Lipoxygenase Antagonist Zileuton Protects Mice from Postoperative Ileus.
A 5-Lipoxygenase Inhibitor, Zileuton, Modulates Host Immune Responses and Improves Lung Function in …
Zileuton ameliorates aminoglycoside and polymyxin-associated acute kidney injury in an animal model.
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Clinical Trials
Most Relevant Clinical Trials
Zileuton With or Without Celecoxib As Chemopreventive Agents in Smokers
Evaluating the Safety of Zileuton (Zyflo®) in Combination With Dasatinib (Sprycel®) in Chronic Myelo…
Aspirin and Zileuton and Biomarker Expression in Nasal Tissue of Current Smokers
Zileuton for the Treatment of Idiopathic Pulmonary Fibrosis
Trial of Zileuton CR in Children and Adults With Sickle Cell Disease
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