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QuickView for JNK cascade (biogroup)


Body Atlas

Most Correlated Tissues

  1. Heart atrium
  2. Kidney medulla
  3. Omental adipose tissue
  4. Prostate gland
  5. Coronary artery
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Disease Atlas

Most Correlated Diseases

  1. Alpha-1-antitrypsin deficiency
  2. Disorder of digestive system
  3. Hemorrhagic shock
  4. Legionella infection
  5. Disease due to Orthopoxvirus
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Pharmaco Atlas

Most Correlated Compounds

  1. KW 2449
  2. ARQ 197
  3. FR 180204
  4. N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine
  5. tivozanib
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. PCDH11X
  2. ANKRD2
  3. FUBP3
  4. CAMK1
  5. MIR125B2
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Prostate cancer PC3.101 cells with CRISPR-targeted gene knockouts
  2. L1000 CMAP - Embryonic stem HUES3 cells treated with small molecule perturbagens
  3. L1000 CMAP - Pancreatic cancer YAPC.311 cells with CRISPR-targeted gene knockouts
  4. L1000 CMAP - Melanoma A375 cells with CRISPR-targeted gene knockouts
  5. L1000 CMAP - Motor neuron MNEU.E cells treated with small molecule perturbagens
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Literature

Most Relevant Literature

  1. Lose and gain: impacts of ERK5 and JNK cascades on each other.
  2. Critical role of the JNK-p53-GADD45α apoptotic cascade in mediating oxidative cytotoxicity in hippoc…
  3. Dynamic modeling and simulation of JNK and P38 kinase cascades with feedbacks and crosstalks.
  4. Computational prediction and analysis of impact of the cross-talks between JNK and P38 kinase cascad…
  5. Analysis of the impact of ERK5, JNK, and P38 kinase cascades on each other: a systems approach.
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Clinical Trials

Most Relevant Clinical Trials

  1. Anti-oxidative Influence From Pomegranate Tablets on Male Sperm Quality in Couples Undergo Infertili…
  2. Pomegranate to Reduce Maternal and Fetal Oxidative Stress and Improve Outcome in Pregnancies Complic…
  3. Therapeutic Hypothermia for Severe Acute Pancreatitis
  4. Hesperidin and Diosmin for Treatment of COVID-19
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