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regulation of isotype switching
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Summary
General Info
Body Atlas
Most Correlated Tissues
Thymus gland
Bone marrow
Kidney cortex
Nipple cross-section
Tonsil
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Disease Atlas
Most Correlated Diseases
Alpha-1-antitrypsin deficiency
Vesicular stomatitis Indiana virus disease
Contact dermatitis
Meningitis
Perforation of tympanic membrane
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Pharmaco Atlas
Most Correlated Compounds
P79 protein, human
((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide)
combretastatin A-4
A 443654
VX-745
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Knockdown Atlas
Most Correlated Gene Perturbations
DROSHA
ANKRD2
FUBP3
PPP2R2C
PTPN6
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Cervical cancer HELA.311 cells with CRISPR induced gene knockouts
L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
Liver gene expression in mice exposed daily to benzo[a]pyrene (BaP)
L1000 CMAP - Bone marrow CD34 cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
Role of B-cell-activating-factor in immune regulation--review].
Regulation of isotype switching.
Cytokine regulation of immunoglobulin isotype switching and expression.
Exaggerated systemic antibody response to mucosal Helicobacter pylori infection in IgA nephropathy.
Mechanism and regulation of immunoglobulin isotype switching.
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Clinical Trials
Most Relevant Clinical Trials
Interferon Responses in Eczema Herpeticum
Aerosol Combination Therapy of All-trans Retinoic Acid and Isotretinoin as A Novel Treatment for Ind…
Anti-PD-1 Monoclonal Antibody in Advanced, Trastuzumab-resistant, HER2-positive Breast Cancer
Pembrolizumab And Tamoxifen Among Women With Advanced Hormone Receptor Positive Breast Cancer And Es…
Pembrolizumab and Induction Chemotherapy in Head and Neck Squamous Cell Carcinoma (PICH Study)
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