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Correlation Engine 2.0
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QuickView for cGMP-stimulated cyclic-nucleotide phosphodiesterase activity (biogroup)


Body Atlas

Most Correlated Tissues

  1. Putamen
  2. Caudate nucleus
  3. Accumbens
  4. Caudate
  5. Tongue superior part with papillae
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Disease Atlas

Most Correlated Diseases

  1. Ataxia-telangiectasia syndrome
  2. Vesicular stomatitis Indiana virus disease
  3. Pyloric ulcer
  4. Viral carditis
  5. Disease due to Enterovirus
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Pharmaco Atlas

Most Correlated Compounds

  1. CP 724714
  2. cyclopiazonic acid
  3. HX 630
  4. CYT 387
  5. BMS 777607
Explore Pharmaco Atlas Results

Knockdown Atlas

Most Correlated Gene Perturbations

  1. RAPGEF3
  2. TRPS1
  3. PLN
  4. ELF3
  5. CSF3R
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Adipose MSC ASC52telo cells with shRNA-mediated gene knockdown
  2. Microglia or peritoneal cells of CX3CR1-deficient mice treated with lipopolysaccharide
  3. L1000 CMAP - Colorectal cancer DLD-1 cells with shRNA-mediated gene knockdown
  4. L1000 CMAP - T-ALL Jurkat cells with shRNA-mediated gene knockdown
  5. Chronic myelogenous leukemia HAP1 cells with WAPL and SCC4 double knockout
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Literature

Most Relevant Literature

  1. Selective inhibition of two soluble adenosine cyclic 3',5'-phosphate phosphodiesterases partially pu…
  2. The identification and characterization of two cyclic nucleotide phosphodiesterases from bovine adre…
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Clinical Trials

Most Relevant Clinical Trials

  1. Does a Nasal Instillation of Vardenafil Normalize the Nasal Potential Difference in Cystic Fibrosis …
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