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2'-5'-oligoadenylate synthetase activity
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
No tissues found
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Disease Atlas
Most Correlated Diseases
Coronavirus infection
Viral enteritis
Influenza
Disease due to Flaviviridae
Severe acute respiratory syndrome
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Pharmaco Atlas
Most Correlated Compounds
DEC-205 receptor
5'PPP-RNA
CL097 compound
interferon beta-1b
HIV Protease Inhibitors
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Knockdown Atlas
Most Correlated Gene Perturbations
SAMHD1
NR2E3
MTAP
IRF7
TOPBP1
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Curated Studies
Most Correlated Studies
HSF1 null and WT fibroblasts co-cultured with breast cancer cells
Macrophage cell line RAW 264.7 cells treated with beta-hematin or 4-hydroxy-2-nonenal
Breast cancer 4T1.2 cell line overexpressing IRF7
Fetal liver of E12.5d old embryos with ADAR1-E861A (editing-deficient mutant of ADAR1 )
Raw264.7 macrophage gene expression profiles in reponse to paeony root-derived compounds
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Literature
Most Relevant Literature
In vivo interferon system assessed by 2'-5' oligoadenylate synthetase activity in chronic hepatitis …
Clinical utility of 2',5'-oligoadenylate synthetase activity measurement: using whole blood as a hig…
Diagnostic evaluation of 2', 5'-oligoadenylate synthetase activities and antibodies against Epstein-…
A bioassay for serum interferon based on induction of 2'5'-oligoadenylate synthetase activity.
Effect of alpha interferon (IFN-alpha) on 2'-5' oligoadenylate synthetase activity in peripheral blo…
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Clinical Trials
Most Relevant Clinical Trials
Single Dose Escalation Study of P1101 in Healthy Adult Male Subjects
Comparative Pharmacokinetics and Pharmacodynamics of Peginterferon BIP48 and 40kDa in Healthy Volunt…
Hepatitis C in Clinically Discordant Hemophilic Siblings
Study of PEG-rIL-29 (or PEG-IFN Lambda) in Subjects With Chronic Hepatitis C Virus Infection
Rintatolimod and IFN Alpha-2b for the Treatment of COVID-19 in Cancer Patients
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