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spindle checkpoint
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Summary
General Info
Body Atlas
Most Correlated Tissues
Thymus gland
Tonsil
Salivary gland
Testes
Bone marrow
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Disease Atlas
Most Correlated Diseases
Social environment related disease
Meningitis
Viral infections of the central nervous system
Bacterial septicemia
Vesicular stomatitis Indiana virus disease
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Pharmaco Atlas
Most Correlated Compounds
TIC10
valrubicin
PHA 793887
enterotoxin F, Staphylococcal
PF 3758309
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Knockdown Atlas
Most Correlated Gene Perturbations
Mir378a
AURKB
RAP1A
NOP2
RPS6
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Curated Studies
Most Correlated Studies
The Immunological Genome Project - Immune cell lineage differentiation and maturation
L1000 CMAP - Umbilical vein endothelial HUVEC cells treated with small molecule perturbagens
Embryonic fibroblasts with N-terminal truncation of Lats1 expression profile
L1000 CMAP - Prostate cancer LNCAP cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature
Most Relevant Literature
Bub1-mediated adaptation of the spindle checkpoint.
Bub1 and BubR1: at the interface between chromosome attachment and the spindle checkpoint.
Aurora-B mediated ATM serine 1403 phosphorylation is required for mitotic ATM activation and the spi…
Mutual regulation between the spindle checkpoint and APC/C.
Centromere-tethered Mps1 pombe homolog (Mph1) kinase is a sufficient marker for recruitment of the s…
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Clinical Trials
Most Relevant Clinical Trials
Doxorubicin Plus Dual Checkpoint Blockade for Soft Tissue Sarcomas
TNF-Inhibitor as Immune Checkpoint Inhibitor for Advanced MELanoma
Alisertib in Chemotherapy-pretreated Urothelial Cancer
Phase I Dose Escalation and Expansion of Oral BAY 1143269 in Combination With Intravenous Docetaxel
Phase I Dose Escalation of Oral BAY1161909 in Combination With Intravenous Paclitaxel
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