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hydroxymethylglutaryl-CoA reductase activity
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General Info
Body Atlas
Most Correlated Tissues
Penis
Vulva
Adrenal gland cortex
Skin
Oral mucosa
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Disease Atlas
Most Correlated Diseases
Hemorrhagic shock
Finding related to sleep
Microbial culture finding
Cholesterol level - finding
Polymyositis
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Pharmaco Atlas
Most Correlated Compounds
rosuvastatin
Complement C1q
Apolipoprotein A-I
amitraz
tetrandrine
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Most Correlated Gene Perturbations
SAR1A
SLC35B1
TAL2
PEBP1
DBI
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Curated Studies
Most Correlated Studies
Drug target sets for approved compounds
OMIM - Cholesterol level
OMIM - Muscular dystrophy
L1000 CMAP Colorectal cancer HT 29 cells with gene overexpression perturbations
Drug Matrix In Vivo Toxicogenomic Study - Rat Liver [Codelink]
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Literature
Most Relevant Literature
Dietary coenzyme Q10 suppressed hepatic hydroxymethylglutaryl-CoA reductase activity in laying hens.
Lipid metabolism in ethanol-treated rat pups and adults: effects of folic Acid.
Hydroxymethylglutaryl-CoA reductase (NADPH) activity in rat brain during development.
Effect of blackgram fiber (Phaseolus mungo) on hepatic hydroxymethylglutaryl-CoA reductase activity,…
Inhibition of cholesterol biosynthesis in primary cultured rat hepatocytes by artichoke (Cynara scol…
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Clinical Trials
Most Relevant Clinical Trials
The Effect of HMG-CoA Reductase Inhibition on Postprandial GLP-1 Secretion
Effect of Probucol and/or Cilostazol on Mean IMT in Patients With Coronary Heart dIsease
Virtual Histology Findings and Effects of Varying Doses of Atorvastatin Treatment
Efficacy and Safety of Pitavastatin and PCSK9 Inhibitors in Liver Transplant Patients
Intensive Glycemic Control and Skeletal Health Study
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