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aspartoacylase activity
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Body Atlas
Most Correlated Tissues
Corpus callosum
Trigeminal ganglia
Kidney cortex
Nodose nucleus
Frontal cortex
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Disease Atlas
Most Correlated Diseases
Prion disease
Multiple organ failure
Alpha-1-antitrypsin deficiency
Liver transplant disorder
Disorder of digestive system
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Pharmaco Atlas
Most Correlated Compounds
Inosine
3MC
RNA
PD 98059
desloratadine
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Knockdown Atlas
Most Correlated Gene Perturbations
TINCR
SMN2
PRKG1
SMN2
HPS1
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Curated Studies
Most Correlated Studies
OMIM - Canavan disease
OMIM - Congenital disorder
Mouse Phenotypes - Canavan's disease
Lung tumor and adjacent normal tissues from patients with HIV-associated lung adenocarcinoma
Uveal melanomas with differential syntenin-1 expression and other clinical attributes
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Literature
Most Relevant Literature
Upregulation of aspartoacylase activity in the duodenum of obesity induced diabetes mouse: implicati…
Lack of aspartoacylase activity disrupts survival and differentiation of neural progenitors and olig…
Restoration of aspartoacylase activity in CNS neurons does not ameliorate motor deficits and demyeli…
A radiometric assay for aspartoacylase activity in cultured oligodendrocytes.
Novel role for aspartoacylase in regulation of BDNF and timing of postnatal oligodendrogenesis.
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Clinical Trials
Most Relevant Clinical Trials
GTA-Glyceryltriacetate for Canavan Disease
rAAV-Olig001-ASPA Gene Therapy for Treatment of Children With Typical Canavan Disease
A Study of AAV9 Gene Therapy in Participants With Canavan Disease
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