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telomerase holoenzyme complex
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Summary
General Info
Body Atlas
Most Correlated Tissues
Tonsil
Thymus gland
Heart ventricle
Hematopoietic stem cell of bone marrow
Trigeminal ganglia
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Disease Atlas
Most Correlated Diseases
Alpha-1-antitrypsin deficiency
Placental insufficiency
Sepsis due to coagulase negative Staphylococcus
Vesicular stomatitis Indiana virus disease
Disorder of digestive system
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Pharmaco Atlas
Most Correlated Compounds
CP 724714
Apitolisib
CGP 60474
AZD8055
GSK-1059615
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Knockdown Atlas
Most Correlated Gene Perturbations
CTNNBIP1
STRAP
FUBP3
NOP2
TLK2
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
L1000 CMAP - Neural progenitor NPC cells treated with small molecule perturbagens
L1000 CMAP - Non-small cell lung cancer A549.311 cells with CRISPR targeted gene knockouts
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature
Most Relevant Literature
Tracing the path of DNA substrates in active Tetrahymena telomerase holoenzyme complexes: mapping of…
Mapping of DNA binding sites in the Tetrahymena telomerase holoenzyme proteins by UV cross-linking a…
Telomerase and cancer.
Telomerase as a therapeutic target for malignant gliomas.
Telomerase as a prognostic marker in breast cancer: high-throughput tissue microarray analysis of hT…
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Clinical Trials
Most Relevant Clinical Trials
Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic Anemia
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