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QuickView for termination of RNA polymerase II transcription (biogroup)


Body Atlas

Most Correlated Tissues

  1. Thymus gland
  2. Dorsal root ganglia
  3. Tonsil
  4. Trigeminal ganglia
  5. Testes
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Disease Atlas

Most Correlated Diseases

  1. Sepsis due to coagulase negative Staphylococcus
  2. Rhinitis
  3. Placental insufficiency
  4. Hemorrhagic shock
  5. Systemic infection
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Pharmaco Atlas

Most Correlated Compounds

  1. N,N-dimethylarginine
  2. CGP 60474
  3. flavopiridol
  4. N-(2-aminophenyl)-4-((4-pyridin-3-ylpyrimidin-2-ylamino)methyl)benzamide
  5. AT 7519
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. DROSHA
  2. AURKB
  3. PMM2
  4. SP110
  5. FUBP3
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Neural progenitor NPC.CAS9 cells treated with small molecule perturbagens
  2. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
  3. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
  4. L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
  5. A375, A549, H3122, PC-9, NCI-N87 and RT-112 cells treated with THZ1 and/or tyrosine kinase inhibitor
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Literature

Most Relevant Literature

  1. Overlapping pathways dictate termination of RNA polymerase II transcription.
  2. Premature termination of RNA polymerase II mediated transcription of a seed protein gene in Schizosa…
  3. The multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3' proce…
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Clinical Trials

Most Relevant Clinical Trials

  1. Messenger RNA (mRNA)-Based, Personalized Cancer Vaccine Against Neoantigens Expressed by the Autolog…
  2. Clinical Performance of Abbott RealTime Hepatitis C Virus (HCV) Genotype II Test
  3. Randomized Phase II Study of Hepatitis C Immune Globulin Intravenous (Human), Civacir(TM), in Liver …
  4. Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors
  5. A Study to Test BI 767551 in People With Mild to Moderate Symptoms of COVID-19
Explore Clinical Trials Results
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