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Correlation Engine 2.0
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(e.g. Kidney, Avian flu virus, Doxorubicin, rs6983267, PBX1, nitric oxide metabolic process)
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QuickView for activation of Janus kinase activity (biogroup)


Body Atlas

Most Correlated Tissues

  1. Colon mucosa
  2. Ventral tegmental area
  3. Nodose nucleus
  4. Substantia nigra
  5. Cervix
Explore Body Atlas Results

Disease Atlas

Most Correlated Diseases

  1. Alpha-1-antitrypsin deficiency
  2. Budd-Chiari syndrome
  3. Disorder of digestive system
  4. Perforation of tympanic membrane
  5. Septicemia due to Enterococcus
Explore Disease Atlas Results

Pharmaco Atlas

Most Correlated Compounds

  1. Valine
  2. combretastatin A-4
  3. CYT 387
  4. CGP 60474
  5. A 443654
Explore Pharmaco Atlas Results

Knockdown Atlas

Most Correlated Gene Perturbations

  1. ARHGAP31
  2. PCDH11X
  3. HAND1
  4. SEPT4
  5. TSC2
Explore Knockdown Atlas Results

Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
  2. L1000 CMAP - Neuronal NEU cells treated with small molecule perturbagens
  3. L1000 CMAP - Prostate cancer LNCAP cells treated with small molecule perturbagens
  4. L1000 CMAP - Bone marrow CD34 cells treated with small molecule perturbagens
  5. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
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Literature

Most Relevant Literature

  1. Aspirin and salicylates inhibit the IL-4- and IL-13-induced activation of STAT6.
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Clinical Trials

Most Relevant Clinical Trials

  1. Study to Evaluate Activity of 2 Dose Levels of Imetelstat in Participants With Intermediate-2 or Hig…
  2. Identification of Biomarkers of Janus Kinase Inhibitor Therapy in Patients With Ulcerative Colitis
  3. Efficacy and Safety of GSK3196165 (Otilimab) Versus Placebo and Sarilumab in Participants With Moder…
  4. Evaluation of Janus Kinase_3 in Juvenile Onset Systemic Lupus Erythematosus
  5. Polymorphism of Janus Kinase 1 and 2 (JAK 1&2) in Patients With Alopecia Areata
Explore Clinical Trials Results
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