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Cdc73/Paf1 complex
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Cervix
Lung
Olfactory bulb
Prostate gland
Peritoneum
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Disease Atlas
Most Correlated Diseases
Zellweger syndrome
Varicella-zoster virus infection
Disorder of peroxisomal function
Bacterial pneumonia
Multiple-resistant Staphylococcus aureus infection
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Pharmaco Atlas
Most Correlated Compounds
epothilone B
CGP 60474
flavopiridol
NVP-AEW541
VX-745
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Knockdown Atlas
Most Correlated Gene Perturbations
RAD61
Ets97D
KRT80
FZD5
NOP2
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Curated Studies
Most Correlated Studies
Carcinoma Associated Fibroblasts and stroma of Non-small cell lung cancer tumors
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
L1000 CMAP - Neural progenitor NPC.CAS9 cells treated with small molecule perturbagens
L1000 CMAP - Neuronal NEU cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 …
Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD…
Cdc73 suppresses genome instability by mediating telomere homeostasis.
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Clinical Trials
Most Relevant Clinical Trials
There were no clinical trials for Cdc73/Paf1 complex
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