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endothelin receptor activity
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Summary
General Info
Body Atlas
Most Correlated Tissues
Lung
Vagina
Pericardium
Cervix
Adipose tissue subcutaneous
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Disease Atlas
Most Correlated Diseases
Microbial culture finding
Immunoglobulin G4 deficiency
Multiple organ dysfunction syndrome
Myocardial ischemia
Infection due to Citrobacter
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Pharmaco Atlas
Most Correlated Compounds
bosentan
4-nitrobenzoic acid
Chlortetracycline
Gonadotropins, Equine
Digitoxin
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Knockdown Atlas
Most Correlated Gene Perturbations
FOXP2
CHMP2B
MAPK6
ACVR1
NR5A1
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Curated Studies
Most Correlated Studies
Drug target sets for approved compounds
L1000 CMAP Colorectal cancer HT 29 cells with gene overexpression perturbations
Neuroepithelial progenitors differentiated from ESCs and treated with toxicants
L1000 CMAP Prostate cancer PC3 cells with gene overexpression perturbations (2 of 2)
Drug Matrix In Vivo Toxicogenomic Study - Rat Kidney [Codelink]
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Literature
Most Relevant Literature
Immunohistochemical localisation of endothelin receptor subtypes in the cochlear lateral wall.
Hybrid peptides constructed from RES-701-1, an endothelin B receptor antagonist, and endothelin; bin…
ETB receptor activation leads to activation and phosphorylation of NHE3.
Characterization of endothelin receptors and endothelin-converting enzyme activity in the rabbit lun…
Important role of C-terminal peptide bonds for endothelin receptor binding and activity.
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Clinical Trials
Most Relevant Clinical Trials
Endothelin-Receptor Blockade in Coronary Heart Disease
Nebivolol and the Endothelin (ET)-1 System
The Effect of Endothelin and L-Arginine on Racial Differences in Vasoconstriction
Endothelin Receptor Blockade in Acute ST-elevation Myocardial Infarction
Role of Endothelin in Microvascular Dysfunction Following PCI for NSTEMI
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