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3',5'-cyclic-nucleotide phosphodiesterase activity
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Heart
Oral mucosa
Parietal lobe
Heart atrium
Nipple cross-section
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Disease Atlas
Most Correlated Diseases
Pyloric ulcer
Vesicular stomatitis Indiana virus disease
Helicobacter pylori gastrointestinal tract infection
Myocardial ischemia
Ulceration of intestine
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Pharmaco Atlas
Most Correlated Compounds
CP 724714
CGP 60474
flavopiridol
A 443654
AT 7519
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Knockdown Atlas
Most Correlated Gene Perturbations
DROSHA
PPP2R2C
POLB
NR5A1
PDE6B
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Curated Studies
Most Correlated Studies
L1000 CMAP - Bone marrow CD34 cells treated with small molecule perturbagens
L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
L1000 CMAP - Breast adenocarcinoma SKBR3 cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Prostate cancer LNCAP cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
Characterization of 3',5' cyclic nucleotide phosphodiesterase activity in Y79 retinoblastoma cells: …
Induction of cyclic AMP and cyclic GMP 3':5'-cyclic nucleotide phosphodiesterase activities in neuro…
Activation of rat cerebral cortical 3',5'-cyclic nucleotide phosphodiesterase activity by gangliosid…
Characterization of 3':5' cyclic nucleotide phosphodiesterase activities of mouse neuroblastoma N18T…
3':5'-cyclic nucleotide phosphodiesterase activity in mammalian tissues.
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Clinical Trials
Most Relevant Clinical Trials
The Phosphodiesterase Inhibitor Pentoxifylline as an Adjuvant in Treatment of Negative Symptoms in C…
Phosphodiesterase 5 Inhibitors (PDE5i) (Sildenafil) as Medical Expulsive Therapy in Distal Ureteral …
PET Whole Body Biodistribution and Test Retest Bain Imaging Studies Using a Phosphodiesterase 4 Inhi…
Appetite Suppression Effects of an Herbal Combination of Yerba maté, Guarana, Damiana (YGD), and 12 …
Treprostinil Combined With Tadalafil for Pulmonary Hypertension
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