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toll-like receptor 4 signaling pathway
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Summary
General Info
Body Atlas
Most Correlated Tissues
Microglial cell
Testes
Monocyte of peripheral blood
Cerebellum
Leukocyte (polymorphonuclear) of peripheral blood
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Disease Atlas
Most Correlated Diseases
Sepsis due to coagulase negative Staphylococcus
Herpes simplex type 2 infection
Bacterial infection of skin
Cryptococcosis
Infection due to Staphylococcus aureus
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Pharmaco Atlas
Most Correlated Compounds
Prnp protein, mouse
PCI 24781
DLL4 protein, human
CGP 60474
AT 7519
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Knockdown Atlas
Most Correlated Gene Perturbations
lsd-1
TIRAP
LAT
TAL2
Relb
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Curated Studies
Most Correlated Studies
Adipose tissue, adipocytes and stromal-vascular pellet cells from multiple body regions
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Adipocyte ASC cells treated with small molecule perturbagens
L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
Effects of eccentric exercise on toll-like receptor 4 signaling pathway in peripheral blood mononucl…
Chlorogenic acid reduces liver inflammation and fibrosis through inhibition of toll-like receptor 4 …
Toll-like receptor 4 signalling pathway activation in a rat model of Acanthamoeba Keratitis.
TRAF6 as the key adaptor of TLR4 signaling pathway is involved in acute pancreatitis.
A glycoprotein from Porphyra yezoensis produces anti-inflammatory effects in liposaccharide-stimulat…
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Clinical Trials
Most Relevant Clinical Trials
Study of the Activation of Proinflammatory Pathways of Toll-like Receptors in Schizophrenia Patients
Probiotics and Systemic Inflammation in Patients With Metabolic Syndrome and High Cardiovascular Ris…
IRAK 4 Inhibitor (PF-06650833) in Hospitalized Patients With COVID-19 Pneumonia and Exuberant Inflam…
Low-Dose Naltrexone (LDN) and Acetaminophen Combination and Its Components in the Acute Treatment of…
Toll-like Receptor 2 Gene Polymorphism, Serum Cytokines and Susceptibility to Disease Severity or Tr…
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