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QuickView for isotype switching (biogroup)


Body Atlas

Most Correlated Tissues

  1. Colon
  2. Tonsil
  3. Ileum mucosa
  4. Coronary artery
  5. Kidney cortex
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Disease Atlas

Most Correlated Diseases

  1. Bacterial septicemia
  2. Pyloric ulcer
  3. Vesicular stomatitis Indiana virus disease
  4. Poisoning by drug AND/OR medicinal substance
  5. Anal penetration by penis
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Pharmaco Atlas

Most Correlated Compounds

  1. enterotoxin F, Staphylococcal
  2. Butylhydroxybutylnitrosamine
  3. Antibodies, Neutralizing
  4. 5-(6)-carboxyfluorescein diacetate succinimidyl ester
  5. CD69 antigen
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. ECD
  2. PPP2R2C
  3. IL10RB
  4. EDA
  5. IGH
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Curated Studies

Most Correlated Studies

  1. B cell and PBMC co-cultures stimulated with anti-IgM and superantigens
  2. L1000 CMAP - Melanoma A375 cells with CRISPR-targeted gene knockouts
  3. Peripheral blood mononuclear cells treated with TCR activators and calcium signaling inhibitors
  4. Prednisolone therapy in children and adolescents with dengue
  5. L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
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Literature

Most Relevant Literature

  1. Shark IgW C Region Diversification through RNA Processing and Isotype Switching.
  2. Arginine methylation regulates antibody responses through modulating cell division and isotype switc…
  3. Separation of function between isotype switching and affinity maturation in vivo during acute immune…
  4. Vitamin C acts indirectly to modulate isotype switching in mouse B cells.
  5. iNOS potentiates mouse Ig isotype switching through AID expression.
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Clinical Trials

Most Relevant Clinical Trials

  1. Correlation Study of Isotype Switching and Neutralizing Capacity to the COVID-19 Variants Strain
  2. 2DR Versus 3DR in a Prospective Randomized Controlled Switch Trial
  3. Immune Response in Subjects With Fabry Disease Who Are Switching From Agalsidase Alfa to Agalsidase …
  4. The Use of Bacteriophage Phi X174 to Assess the Immune Competence of HIV-Infected Patients In Vivo
  5. Expression of Ku70/XRCC6 in Waldenström's Macroglobulinemia
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