QuickView for double-stranded telomeric DNA binding (biogroup)

1. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
2. L1000 CMAP - Breast adenocarcinoma SKBR3 cells treated with small molecule perturbagens
3. RAW264.7 macrophages overexpressing Tbc1d23 and/or stimulated with LPS
4. L1000 CMAP - Prostate cancer LNCAP cells treated with small molecule perturbagens
5. L1000 CMAP - Neural progenitor NPC.CAS9 cells treated with small molecule perturbagens

1. Identification of HMG-5 as a double-stranded telomeric DNA-binding protein in the nematode Caenorhab…
2. Comparison between TRF2 and TRF1 of their telomeric DNA-bound structures and DNA-binding activities.
3. Loss of hPot1 function leads to telomere instability and a cut-like phenotype.
4. Structure of the DNA-binding domain of human telomeric protein, TRF1 and its interaction with telome…

There were no clinical trials for double-stranded telomeric DNA binding