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RISC-loading complex
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Summary
General Info
Body Atlas
Most Correlated Tissues
Salivary gland
Cerebellum
Vena cava
Rectum colon
Sigmoid colon
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Disease Atlas
Most Correlated Diseases
Multiple-resistant Staphylococcus aureus infection
Pyloric ulcer
Helicobacter pylori gastrointestinal tract infection
Disorder of pregnancy
Tularemia
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Pharmaco Atlas
Most Correlated Compounds
NVP-AEW541
combretastatin A-4
JM 3100
valrubicin
A-66
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Knockdown Atlas
Most Correlated Gene Perturbations
MIR204
C15orf65
INSM2
CIITA
GRHPR
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
L1000 CMAP - T-cell ALL JURKAT cells treated with small molecule perturbagens
L1000 CMAP - Prostate cancer LNCAP cells treated with small molecule perturbagens
L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
L1000 CMAP - Umbilical vein endothelial HUVEC cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
Structural insights into RNA processing by the human RISC-loading complex.
In vitro reconstitution of the human RISC-loading complex.
Purification and assembly of human Argonaute, Dicer, and TRBP complexes.
The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing.
Intracellular localization and routing of miRNA and RNAi pathway components.
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Clinical Trials
Most Relevant Clinical Trials
Lipid and Glycogen Metabolism in Patients With Impaired Glucose Tolerance and Calcium Sensing Recept…
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