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DNA-dependent protein kinase complex
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Dendritic (plasmacytoid) cell
Adipose tissue subcutaneous
Adipose tissue
B lymphocyte (naive) of spleen
Mammary gland
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Disease Atlas
Most Correlated Diseases
Poisoning by drug AND/OR medicinal substance
Toxic nephropathy
Ebola virus disease
Aspergillosis
Disease due to Trypanosomatidae
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Pharmaco Atlas
Most Correlated Compounds
Deoxycytidine
Zalypsis
Havrix
butyl salicylate
phenethyl isothiocyanate
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Knockdown Atlas
Most Correlated Gene Perturbations
POLE2
PAK1
IGH
GPX1
PRPF4B
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Curated Studies
Most Correlated Studies
L1000 CMAP Breast cancer MCF7 cells with gene overexpression perturbations
Thioxotriazole copper(II) complex A0 and Cisplatin treated HT1080 cells
L1000 CMAP Prostate cancer PC3 cells with gene overexpression perturbations (2 of 2)
L1000 CMAP - Hepatocellular carcinoma Hep G2 cells with shRNA-mediated gene knockdown (1 of 2)
Multiple cancer cell lines treated with 32 kinase inhibitors
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Literature
Most Relevant Literature
DNA-PK-dependent RPA2 hyperphosphorylation facilitates DNA repair and suppresses sister chromatid ex…
Deformed epidermal autoregulatory factor-1 (DEAF1) interacts with the Ku70 subunit of the DNA-depend…
The corepressor silencing mediator for retinoid and thyroid hormone receptor facilitates cellular re…
Chlorambucil cytotoxicity in malignant B lymphocytes is synergistically increased by 2-(morpholin-4-…
Age-related transcription levels of KU70, MGST1 and BIK in CD34+ hematopoietic stem and progenitor c…
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Clinical Trials
Most Relevant Clinical Trials
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics
A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and A…
Vitamin D and Breast Cancer: Does Weight Make a Difference?
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma
The Role of Arachidonic Acid Metabolites, From Patients With Metabolic Syndrome
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