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immunological synapse formation
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
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Disease Atlas
Most Correlated Diseases
Contact dermatitis
Alpha-1-antitrypsin deficiency
Disorder of digestive system
Ulceration of intestine
Chlamydial infection
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Pharmaco Atlas
Most Correlated Compounds
PHA 665752
NPK76 II 72 1
Trinitrobenzenesulfonic Acid
AST-1306
SGX 523
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Knockdown Atlas
Most Correlated Gene Perturbations
MAST4
RIOK2
DROSHA
TNFRSF21
CRKL
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Curated Studies
Most Correlated Studies
L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
Kidney from patients with normal and dysfunctional renal allografts
Hepatocellular carcinoma (HCC): Expression profiles at different stages and grades
L1000 CMAP - T-cell ALL JURKAT cells treated with small molecule perturbagens
L1000 CMAP - Bone marrow CD34 cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
T cell killing does not require the formation of a stable mature immunological synapse.
Lipid rafts mediate association of LFA-1 and CD3 and formation of the immunological synapse of CTL.
The immunological synapse: a focal point for endocytosis and exocytosis.
Can we see PIP(3) and hydrogen peroxide with a single probe?
Cell polarisation and the immunological synapse.
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Clinical Trials
Most Relevant Clinical Trials
First in Human Study of NVG-111 in Chronic Lymphocytic Leukaemia and Mantle Cell Lymphoma
Safety Study to Assess AFM11 in Patients With Relapsed and/or Refractory CD19 Positive B-cell NHL
Safety Study to Assess AFM11 in Patients With Relapsed or Refractory Adult B-precursor ALL
Role of CD11a in Pathogenesis of Primary ITP and Effect of Immunosuppressive Therapy on Its Level
The Potential Role of SI00B and Brain Derived Neurotrophic Factor in Predicting Outcome From Using P…
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