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QuickView for sialic acid binding (biogroup)


Body Atlas

Most Correlated Tissues

  1. Lung
  2. Cerebellum
  3. Colon cecum
  4. Cerebellar vermis
  5. Kidney medulla
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Disease Atlas

Most Correlated Diseases

  1. Bovine respiratory syncytial virus disease
  2. Chronic interstitial cystitis
  3. Periodontitis
  4. Contact dermatitis
  5. Herpes simplex type 2 infection
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Pharmaco Atlas

Most Correlated Compounds

  1. CGP 60474
  2. CP 724714
  3. bosutinib
  4. AT 7867
  5. cabozantinib
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. LEP
  2. FOXP2
  3. JCAD
  4. DIDO1
  5. PPP2R2C
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Embryonic stem HUES3 cells treated with small molecule perturbagens
  2. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
  3. L1000 CMAP - Neural progenitor NPC.CAS9 cells treated with small molecule perturbagens
  4. L1000 CMAP - Umbilical vein endothelial HUVEC cells treated with small molecule perturbagens
  5. L1000 CMAP - Neural progenitor NPC cells treated with small molecule perturbagens
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Literature

Most Relevant Literature

  1. CD22 and Siglec-G in B cell function and tolerance.
  2. A Siglec-like sialic-acid-binding motif revealed in an adenovirus capsid protein.
  3. Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and ind…
  4. Click and pick: identification of sialoside analogues for siglec-based cell targeting.
  5. ITIM-dependent endocytosis of CD33-related Siglecs: role of intracellular domain, tyrosine phosphory…
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Clinical Trials

Most Relevant Clinical Trials

  1. Administration of Anti-siglec-6 CAR-T Cell Therapy in Relapsed and Refractory Acute Myeloid Leukemia…
  2. Biodistribution, Dosimetry and Performance of [68Ga]Ga-DOTA-Siglec-9 in Healthy and Patients With Rh…
  3. "Don't Eat me" Signal in Hematological Malignancies: CD24 as New Target to Improve Anti-cancer Immun…
  4. Decitabine and Gemtuzumab Ozogamicin in Acute Myelogenous Leukemia and High-risk Myelodysplastic Syn…
  5. Allogenic Stem Cell Transplantation in Patients With High Risk CD33+ AML/MDS/JMML
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