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glutamate-cysteine ligase activity
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Summary
General Info
Body Atlas
Most Correlated Tissues
Bronchus
Bone marrow
Trachea
Fetal liver
Ileum mucosa
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Disease Atlas
Most Correlated Diseases
Hypercapnia
Disease due to Rotavirus
Sepsis due to coagulase negative Staphylococcus
Hyperoxia
Injury of lung
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Pharmaco Atlas
Most Correlated Compounds
ONO 2235
scytonemin
Lipids
Anti-HIV Agents
tazobactam
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Knockdown Atlas
Most Correlated Gene Perturbations
SMNDC1
KEAP1
NFATC2
EDA
PCDH11X
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Curated Studies
Most Correlated Studies
Differences in the response to LPS and OxPAPC of macrophages from HMDP mouse strains
OMIM - Heart disease
L1000 CMAP Prostate cancer PC3 cells with gene overexpression perturbations (1 of 2)
Liver spheroids treated with variable doses of per- and polyfluoroalkyl substances (PFAS)
H441 lung adenocarcinoma cells treated with chemotherapeutic drug CLEFMA
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Literature
Most Relevant Literature
The age-related change of glutathione antioxidant system in mice liver.
Inhibition of glutamate cysteine ligase activity sensitizes human breast cancer cells to the toxicit…
Co-culture of neurones with glutathione deficient astrocytes leads to increased neuronal susceptibil…
The difference of glutathione antioxidant system in newly weaned and young mice liver and its involv…
Aging enhances susceptibility to cigarette smoke-induced inflammation through bronchiolar chemokines…
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Clinical Trials
Most Relevant Clinical Trials
Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Adva…
Melatonin in Smoke-induced Vascular Injury
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