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QuickView for mitotic checkpoint complex (biogroup)


Body Atlas

Most Correlated Tissues

  1. T Lymphocyte (regulatory) of peripheral blood
  2. T Lymphocyte (CD8+) of peripheral blood
  3. Pancreas
  4. T Lymphocyte (CD4+) of peripheral blood
  5. Uterus
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Disease Atlas

Most Correlated Diseases

  1. Sepsis due to coagulase negative Staphylococcus
  2. Systemic infection
  3. Sepsis due to Streptococcus agalactiae
  4. Streptococcal infectious disease
  5. Diarrhea
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Pharmaco Atlas

Most Correlated Compounds

  1. Pyrimidines
  2. TIC10
  3. Cantharidin
  4. PIK 75
  5. Hexamethonium
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. moc4
  2. EMC10
  3. U2AF1
  4. TOP2A
  5. MIR142
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Curated Studies

Most Correlated Studies

  1. Yeast knockout (YKO) analysis with dSLAM (diploid-based synthetic lethality analysis on microarrays)
  2. L1000 CMAP Osteosarcoma U-2 OS cells with gene overexpression perturbations
  3. L1000 CMAP - Hepatocellular carcinoma Hep G2 cells with shRNA-mediated gene knockdown (2 of 2)
  4. S.cerevisiae haploid gene expression in response to increasing doses of benomyl
  5. L1000 CMAP Colorectal cancer HT 29 cells with gene overexpression perturbations
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Literature

Most Relevant Literature

  1. Roles of different pools of the mitotic checkpoint complex and the mechanisms of their disassembly.
  2. Closed MAD2 (C-MAD2) is selectively incorporated into the mitotic checkpoint complex (MCC).
  3. Role of phosphorylation of Cdc20 in p31(comet)-stimulated disassembly of the mitotic checkpoint comp…
  4. Purification of the mitotic checkpoint complex (MCC) and the anaphase promoting complex/cyclosome (A…
  5. p31comet Promotes disassembly of the mitotic checkpoint complex in an ATP-dependent process.
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Clinical Trials

Most Relevant Clinical Trials

  1. Evaluation of IPI-549 Combined With Front-line Treatments in Pts. With Triple-Negative Breast Cancer…
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