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FGF21
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AP-3 adaptor complex
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Pituitary gland
Tongue main corpus
Tongue superior part with papillae
Thalamus lateral nuclei
Vena cava
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Disease Atlas
Most Correlated Diseases
Obsessive-compulsive disorder
Pyloric ulcer
Alpha-1-antitrypsin deficiency
Varicella-zoster virus infection
Injury of integument
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Pharmaco Atlas
Most Correlated Compounds
P79 protein, human
CGP 60474
GSK690693
A 443654
Apitolisib
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Knockdown Atlas
Most Correlated Gene Perturbations
Mir30b
MIRLET7D
INSM2
HNRNPA0
GSDME
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Curated Studies
Most Correlated Studies
Pancreatic beta cells derived from acinar cells - Timecourse
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
Breast tumors derived from multipotent breast tumor cell lines after cell-type differentiation
L1000 CMAP - Adipocyte ASC cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7.101 cells with CRISPR targeted gene knockouts
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Literature
Most Relevant Literature
The AP-3 adaptor complex is required for vacuolar function in Arabidopsis.
Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane …
C. elegans Disabled is required for cell-type specific endocytosis and is essential in animals lacki…
A dominant-negative form of Arabidopsis AP-3 β-adaptin improves intracellular pH homeostasis.
BLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32/38 guanine nucleotide exchange factor.
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Clinical Trials
Most Relevant Clinical Trials
Melpida: Recombinant Adeno-associated Virus (Serotype 9) Encoding a Codon Optimized Human AP4M1 Tran…
Plasmodium Falciparum Genomic Intelligence in Mozambique
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