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QuickView for HOPS complex (biogroup)


Body Atlas

Most Correlated Tissues

  1. Liver
  2. Colon cecum
  3. Pituitary gland
  4. Trachea
  5. Skin
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Disease Atlas

Most Correlated Diseases

  1. Pyloric ulcer
  2. Lymphedema
  3. Obsessive-compulsive disorder
  4. Multiple-resistant Staphylococcus aureus infection
  5. Alpha-1-antitrypsin deficiency
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Pharmaco Atlas

Most Correlated Compounds

  1. SB-590885
  2. GSK690693
  3. trinitrophenyl-bovine serum albumin
  4. niguldipine
  5. Apitolisib
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. Idd1
  2. Idd5
  3. INSM2
  4. NUP62
  5. PSCA
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
  2. T regulatory and T effector cells CD3/CD28 stimulation timecourse analysis
  3. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
  4. L1000 CMAP - Neural progenitor NPC.CAS9 cells treated with small molecule perturbagens
  5. L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
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Literature

Most Relevant Literature

  1. The hookup model of the HOPS complex in autophagosome-lysosome fusion.
  2. Loss of the HOPS complex disrupts early-to-late endosome transition, impairs endosomal recycling and…
  3. The Drosophila ZNRF1/2 homologue, detour, interacts with HOPS complex and regulates autophagy.
  4. The HOPS complex subunit VPS39 controls ciliogenesis through autophagy.
  5. Bi-allelic variants in HOPS complex subunit VPS41 cause cerebellar ataxia and abnormal membrane traf…
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Clinical Trials

Most Relevant Clinical Trials

  1. Old SCHOOL Hip-Hop: Improve Alzheimer's Disease Knowledge
  2. Plyometric and Complex Training in Male Cricket Players
  3. Reversal of Dabigatran With Prothrombin Complex Concentrate
  4. Impact of Inhaled PT003 on Complexity and Variability of Tidal Breathing and Oscillatory Mechanics i…
  5. Effect of NT 201 (Botulinum Neurotoxin Type A Free of Complexing Proteins) on Sleep-related Breathin…
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