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cGMP binding
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Summary
General Info
Body Atlas
Most Correlated Tissues
Oral mucosa
Pharyngeal mucosa
Caudate nucleus
Extraocular muscle
Heart
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Disease Atlas
Most Correlated Diseases
Helicobacter pylori gastrointestinal tract infection
Pyloric ulcer
Retinal detachment
Vesicular stomatitis Indiana virus disease
Stachybotryotoxicosis
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Pharmaco Atlas
Most Correlated Compounds
CGP 60474
Glesatinib
A 443654
Apitolisib
sunitinib
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Knockdown Atlas
Most Correlated Gene Perturbations
UBA52
PPP2R2C
PHKG2
CRX
PRSS2
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Curated Studies
Most Correlated Studies
Retinas from CRX mutant mice with Leber congenital amaurosis phenotype
L1000 CMAP - Neural progenitor NPC.CAS9 cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Umbilical vein endothelial HUVEC cells treated with small molecule perturbagens
L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
Conformational conversion of PDE5 by incubation with sildenafil or metal ion is accompanied by stimu…
Evidence That Binding of Cyclic GMP to the Extracellular Domain of NKA (Sodium-Potassium ATPase) Med…
The GAF domain of the cGMP-binding, cGMP-specific phosphodiesterase (PDE5) is a sensor and a sink fo…
PDGFR-β Promoter Forms a Vacancy G-Quadruplex that Can Be Filled in by dGMP: Solution Structure and …
cGMP-binding prepares PKG for substrate binding by disclosing the C-terminal domain.
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Clinical Trials
Most Relevant Clinical Trials
The Effects of CGMP in Children and Adults With PKU
Effect of Daily Consumption of Glycomacropeptide on Gut Microbiome and Blood Functional Proteome of …
Linaclotide in Treating Patients With Stages 0-3 Colorectal Cancer
Embryo Developmental Potential in a Novel 2-step IVM System
0,9% NaCl Effect on Kidney Function and Glycocalyx in Patients Operated on for Primary Hiparthrosis
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