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mitotic G1 DNA damage checkpoint
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General Info
Body Atlas
Most Correlated Tissues
Substantia nigra reticulata
Substantia nigra
Globus pallidum external
Medulla
Vestibular nuclei superior
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Disease Atlas
Most Correlated Diseases
Pyloric ulcer
Alpha-1-antitrypsin deficiency
Zika virus disease
Myocardial ischemia
Multiple-resistant Staphylococcus aureus infection
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Pharmaco Atlas
Most Correlated Compounds
PHA 793887
flavopiridol
CGP 60474
AT 7519
((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide)
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Knockdown Atlas
Most Correlated Gene Perturbations
SULF1
AURKB
POLH
CDK7
TIRAP
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Curated Studies
Most Correlated Studies
Spatio-temporal transcriptome of the human brain
Lung adenocarcinoma and adjacent normal tissue miRNA expression profiles
Follicular fluid miRNA profiles during the development of the oocyte
miRNA expression profiles from osteosarcoma samples and cell lines
L1000 CMAP - Neural progenitor NPC cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
An essential role for the Saccharomyces cerevisiae DEAD-box helicase DHH1 in G1/S DNA-damage checkpo…
The 70 kDa subunit of replication protein A is required for the G1/S and intra-S DNA damage checkpoi…
Inhibition of Chk1-dependent G2 DNA damage checkpoint radiosensitizes p53 mutant human cells.
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Clinical Trials
Most Relevant Clinical Trials
Durvalumab and Tremelimumab in Combination With Propranolol and Chemotherapy for Treatment of Advanc…
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