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striated muscle contraction
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Body Atlas
Most Correlated Tissues
Heart ventricle
Heart atrium
Heart
Skeletal muscle
Jejunum
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Disease Atlas
Most Correlated Diseases
Pyloric ulcer
Vesicular stomatitis Indiana virus disease
Fibrosis of lung
Duchenne muscular dystrophy
Muscle atrophy
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Pharmaco Atlas
Most Correlated Compounds
CGP 60474
A 443654
AT 7519
flavopiridol
((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide)
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Knockdown Atlas
Most Correlated Gene Perturbations
PPP2R2C
NCL
NR5A1
ELN
MIR206
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
L1000 CMAP - Motor neuron MNEU.E cells treated with small molecule perturbagens
L1000 CMAP - Breast adenocarcinoma SKBR3 cells treated with small molecule perturbagens
L1000 CMAP - Bone marrow CD34 cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature
Most Relevant Literature
Disease causing mutations of troponin alter regulated actin state distributions.
Tropomyosin flexural rigidity and single ca(2+) regulatory unit dynamics: implications for cooperati…
Comparative studies on troponin, a Ca²⁺-dependent regulator of muscle contraction, in striated and s…
Effects of calcium binding and the hypertrophic cardiomyopathy A8V mutation on the dynamic equilibri…
The C-terminus of troponin T is essential for maintaining the inactive state of regulated actin.
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Clinical Trials
Most Relevant Clinical Trials
Safety Demonstration of Increasing Intensities of Electrical Stimulation Delivered to The Bulbospong…
The Muscle in Cerebral Palsy; Sarcomere Length in Vivo and Microscopic Characterization of Biopsies.
iMEA : Comparison of Micro-innervation and Muscle Microstructure of the Anal Levator Muscle Between …
Exercise Frequency During Endurance Training: Cardiorespiratory, Hematological, and Muscle Oxidative…
Multiple Sclerosis and Voiding Symptoms: How to Assess?
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