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Correlation Engine 2.0
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Clear Search sequence regions
(e.g. Diabetes mellitus, Kidney, Amniocentesis, Cisplatin, rs2230926, DRD2)
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QuickView for polyamine metabolic process (biogroup)


Body Atlas

Most Correlated Tissues

  1. Frontal lobe
  2. Skeletal muscle
  3. Jejunum
  4. Kidney medulla
  5. Nipple cross-section
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Disease Atlas

Most Correlated Diseases

  1. Injury of eye region
  2. Injury of integument
  3. Hemorrhagic shock
  4. Bacterial pneumonia
  5. Bacterial infection of skin
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Pharmaco Atlas

Most Correlated Compounds

  1. HX 630
  2. 5-((2,6-dichlorobenzyl)sulfonyl)-3-((3,5-dimethyl-4-((2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-1,3-dihydro-2H-indol-2-one
  3. GDNF protein, human
  4. N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine
  5. tivozanib
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. INSM2
  2. FUBP3
  3. NOP2
  4. IRF7
  5. CTSK
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Curated Studies

Most Correlated Studies

  1. Skin keratinocyte HaCaT cells treated with Ino-C2-PAF and inflammatory cytokines
  2. L1000 CMAP - Kidney epithelial HA1E.101 cells with CRISPR targeted gene knockouts
  3. L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
  4. L1000 CMAP - Melanoma A375 cells with CRISPR-targeted gene knockouts
  5. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
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Literature

Most Relevant Literature

  1. Spermine-enhanced protein phosphorylation in human placenta.
  2. Serosal patching impairs intestinal adaptation following enterectomy.
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Clinical Trials

Most Relevant Clinical Trials

  1. TArgeting Type 1 Diabetes Using POLyamines (TADPOL)
  2. Metabolic Responses to Spermidine Supplementation.
  3. sPERMIdine supplemenTation on Metabolic, Neuronal and Cardiovascular Response to Exercise TRAINING
  4. Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High G…
  5. Urinary Excretion of Acetylamantadine by Normal Healthy Volunteers
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