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QuickView for NAD-dependent protein deacetylase activity (biogroup)


Body Atlas

Most Correlated Tissues

  1. Joint synovium
  2. Adipose tissue
  3. Pericardium
  4. Urethra
  5. Bronchus
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Disease Atlas

Most Correlated Diseases

  1. Pyloric ulcer
  2. Microbial culture finding
  3. Muscle cachexia
  4. Bacterial sepsis of newborn
  5. Adrenal cancer
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Pharmaco Atlas

Most Correlated Compounds

  1. PCI 24781
  2. GSK690693
  3. 4-(4-(trifluoromethyl)phenyl)-N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxamide
  4. combretastatin A-4
  5. GSK-1059615
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. dpy-10
  2. NCL
  3. KCNA1
  4. CRKL
  5. EXO1
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Breast adenocarcinoma SKBR3 cells treated with small molecule perturbagens
  2. L1000 CMAP - Bone marrow CD34 cells treated with small molecule perturbagens
  3. Circulating miRNA in serum of Wilms tumor patients
  4. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
  5. L1000 CMAP - Skeletal muscle SKL.C cells treated with small molecule perturbagens
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Literature

Most Relevant Literature

  1. Pre-B-cell colony-enhancing factor regulates NAD+-dependent protein deacetylase activity and promote…
  2. Characterization of murine SIRT3 transcript variants and corresponding protein products.
  3. Cloning and characterization of NAD-dependent protein deacetylase (Rv1151c) from Mycobacterium tuber…
  4. Chromosomal organization and fluorescence in situ hybridization of the human Sirtuin 6 gene.
  5. Identification of the protein acetyltransferase (Pat) enzyme that acetylates acetyl-CoA synthetase i…
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Clinical Trials

Most Relevant Clinical Trials

  1. Sirtuin-NAD Activator in Alzheimer's Disease
  2. The Effect of Nicotinamide Riboside on Skeletal Muscle Function in Heart Failure Subjects
  3. Electrical Vestibular Stimulation (VeNS): Assessment of AMPK & SIRT1 Following Repeated Usage
  4. Calorie Restriction Retards the Aging Process
  5. Inflammatory Axis and Sirtuins' in Overweight Pre-diabetics Patients
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