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actin cap
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Fetal brain
Kidney
Saphenous vein
Stomach fundus
Stomach pyloric
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Disease Atlas
Most Correlated Diseases
Disorder of pregnancy
Disorder affecting transplanted structure
Ulceration of intestine
Glomerulosclerosis
Perforation of tympanic membrane
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Pharmaco Atlas
Most Correlated Compounds
niguldipine
2-methyl-1-((4-methyl-5-isoquinolinyl)sulfonyl)homopiperazine
AS 1411
4-(4-(trifluoromethyl)phenyl)-N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxamide
Botulinum Toxins
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Knockdown Atlas
Most Correlated Gene Perturbations
Idd1
Idd5
MAGEB6
INSM2
LAMP3
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Curated Studies
Most Correlated Studies
L1000 CMAP - Cervical cancer HELA.311 cells with CRISPR induced gene knockouts
L1000 CMAP - Bone marrow CD34 cells treated with small molecule perturbagens
Oct3-4 overexpression and repression in ES cells
Brain cancer cell lines SW1783 and U87 transfected with 2 forms of miR-376a
L1000 CMAP - Pancreatic cancer YAPC.311 cells with CRISPR-targeted gene knockouts
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Literature
Most Relevant Literature
Aberrant MET activation impairs perinuclear actin cap organization with YAP1 cytosolic relocation.
NLRP4E regulates actin cap formation through SRC and CDC42 during oocyte meiosis.
STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap.
Intersectin 2 controls actin cap formation and meiotic division in mouse oocytes through the Cdc42 p…
Tight coupling between nucleus and cell migration through the perinuclear actin cap.
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Clinical Trials
Most Relevant Clinical Trials
Cryosurgery and Cream Combination for Actinic Keratosis
Clinical Trial of Ingenol Mebutate Gel 0.015% & 0.05% in Actinic Keratosis
Efficacy and Safety of a New Topical Formulation With Imiquimod (Limtop) Applied 1, 3 or 7 Times Wee…
Congenital Muscle Disease Study of Patient and Family Reported Medical Information
Comparison of Two Modes of Photodynamic Therapy for the Treatment of Actinic Keratosis on the Upper …
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