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regulation of DNA damage checkpoint
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Body Atlas
Most Correlated Tissues
Hypothalamus
Medulla oblongata
Vestibular nuclei superior
Parietal lobe
Vagina
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Disease Atlas
Most Correlated Diseases
No diseases found
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Pharmaco Atlas
Most Correlated Compounds
No compounds found
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Knockdown Atlas
Most Correlated Gene Perturbations
No perturbed genes found
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Curated Studies
Most Correlated Studies
L1000 CMAP - Embryonic stem HUES3 cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Breast cancer MCF7.311 cells with CRISPR-induced gene knockouts
Embryonic stem cell differentiation timecourse analysis via LIF withdrawal
The Immunological Genome Project - Immune cell lineage differentiation and maturation
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Literature
Most Relevant Literature
Structural delineation of MDC1-FHA domain binding with CHK2-pThr68.
WD40-repeat protein WDR18 collaborates with TopBP1 to facilitate DNA damage checkpoint signaling.
Mechanism of regulation of hepatoma cell cycle by XPD/P44 subcomplex : an in vitro experiment].
Genotoxic stress-induced activation of Plk3 is partly mediated by Chk2.
atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute …
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Clinical Trials
Most Relevant Clinical Trials
Phase II, Single-arm Study of AZD1775 Monotherapy in Relapsed Small Cell Lung Cancer Patients With M…
Phase II, Single-arm Study of AZD1775 Monotherapy in Relapsed Small Cell Lung Cancer Patients
Low-Dose Radiation Therapy to the Whole Liver With Gemcitabine and Cisplatin in IHC
Cetuximab Plus Dalpicilib in Patients With HPV Negative, PD-1 Resistant R/M HNSCC
Regorafenib Combined With PD-1 Inhibitor Therapy for Second-line Treatment of Hepatocellular Carcino…
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