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NAD-dependent protein deacetylase activity
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Joint synovium
Adipose tissue
Pericardium
Urethra
Bronchus
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Disease Atlas
Most Correlated Diseases
Pyloric ulcer
Microbial culture finding
Muscle cachexia
Bacterial sepsis of newborn
Adrenal cancer
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Pharmaco Atlas
Most Correlated Compounds
PCI 24781
GSK690693
4-(4-(trifluoromethyl)phenyl)-N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxamide
combretastatin A-4
GSK-1059615
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Knockdown Atlas
Most Correlated Gene Perturbations
dpy-10
NCL
KCNA1
CRKL
EXO1
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast adenocarcinoma SKBR3 cells treated with small molecule perturbagens
L1000 CMAP - Bone marrow CD34 cells treated with small molecule perturbagens
Circulating miRNA in serum of Wilms tumor patients
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Skeletal muscle SKL.C cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
Pre-B-cell colony-enhancing factor regulates NAD+-dependent protein deacetylase activity and promote…
Characterization of murine SIRT3 transcript variants and corresponding protein products.
Cloning and characterization of NAD-dependent protein deacetylase (Rv1151c) from Mycobacterium tuber…
Chromosomal organization and fluorescence in situ hybridization of the human Sirtuin 6 gene.
Identification of the protein acetyltransferase (Pat) enzyme that acetylates acetyl-CoA synthetase i…
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Clinical Trials
Most Relevant Clinical Trials
Sirtuin-NAD Activator in Alzheimer's Disease
The Effect of Nicotinamide Riboside on Skeletal Muscle Function in Heart Failure Subjects
Electrical Vestibular Stimulation (VeNS): Assessment of AMPK & SIRT1 Following Repeated Usage
Calorie Restriction Retards the Aging Process
Inflammatory Axis and Sirtuins' in Overweight Pre-diabetics Patients
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