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dihydrofolate reductase activity
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Thymus gland
Nodose nucleus
Corpus callosum
Pancreas
Salivary gland
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Disease Atlas
Most Correlated Diseases
Zika virus disease
Adverse reaction to drug
Rhinitis
Protozoan infection
Immunoglobulin G4 deficiency
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Pharmaco Atlas
Most Correlated Compounds
Trimetrexate
pemetrexed
Isoleucine
Dinitrophenols
AZD 1152
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Knockdown Atlas
Most Correlated Gene Perturbations
SET2
36431
MIRLET7A3
MIRLET7A2
MIRLET7A1
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Curated Studies
Most Correlated Studies
HeLa cells synchronized then released from S and mitosis phases
Ovarian cancer lines transfection with miRNA precursors: let-7f, miR200c, miR424, miR34c, miR98
Induced pluripotent stem cells with ACE2 overexpression and SARS-CoV-2 infection
HEK293 cells transfected with wild type and mutant EBV EBER2
Blood transcriptome variability in postmenopausal women
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Literature
Most Relevant Literature
Regulation of human dihydrofolate reductase activity and expression.
Influence of the antifolate drug Methotrexate on the development of murine neural tube defects and g…
The former annotated human pseudogene dihydrofolate reductase-like 1 (DHFRL1) is expressed and funct…
Methotrexate preconditioning allows sufficient engraftment to confer drug resistance in mice transpl…
Gammaherpesviruses encode functional dihydrofolate reductase activity.
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Clinical Trials
Most Relevant Clinical Trials
A Study to Assess CH1504 in Patients With Active Rheumatoid Arthritis
Pyrimethamine as an Inhibitor of NRF2 in HPV-negative Locally Advanced Head and Neck Squamous Cell C…
Pemetrexed Followed by Docetaxel or in Reverse Sequence
Therapeutic Effect of Folic Acid in Healing of Oral Ulcers
DHFR 19 bp Deletion Polymorphism and Folic Acid Utilization
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