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nuclear pre-replicative complex
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General Info
Body Atlas
Most Correlated Tissues
Stomach cardiac
Ileum mucosa
Testes
Colon mucosa
Hematopoietic stem cell of bone marrow
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Disease Atlas
Most Correlated Diseases
Alpha-1-antitrypsin deficiency
Disorder of digestive system
Placental insufficiency
Bacterial infection due to Bacillus
Dermatosis due to mites
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Pharmaco Atlas
Most Correlated Compounds
enterotoxin F, Staphylococcal
5-(6)-carboxyfluorescein diacetate succinimidyl ester
cumene hydroperoxide
Pyrimidines
valrubicin
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Knockdown Atlas
Most Correlated Gene Perturbations
TAF14
FLO1
NSDHL
CDK7
NUP62
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Curated Studies
Most Correlated Studies
S. cerevisiae oxidative stress response to cumene hydroperoxide (timecourse)
S. cerevisiae benomyl-responsive gene expression in wildtype and aft1 null mutants
Structure and Function of a Transcriptional Network Activated by Hog1
L1000 CMAP - Hepatocellular carcinoma Hep G2 cells with shRNA-mediated gene knockdown (2 of 2)
L1000 CMAP Prostate cancer PC3 cells with gene overexpression perturbations (1 of 2)
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Literature
Most Relevant Literature
Norcantharidin inhibits pre-replicative complexes assembly of HepG2 cells.
Two oppositely oriented arrays of low-affinity recognition sites in oriC guide progressive binding o…
The role of pre-replicative complex (pre-RC) components in oncogenesis.
Genome-wide localization of pre-RC sites and identification of replication origins in fission yeast.
An essential role for Orc6 in DNA replication through maintenance of pre-replicative complexes.
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Clinical Trials
Most Relevant Clinical Trials
Vitamin D Levels in Liver Transplantation Recipients Prospective Observational Study
Aerosol Combination Therapy of All-trans Retinoic Acid and Isotretinoin as A Novel Treatment for Ind…
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With …
Plant Extracted Natural Compounds Impact on Stage IV Breast Cancer Survival Time and Remission.
Expanding Rapid Ascertainment Networks of Schizophrenia Families in Taiwan
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