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QuickView for AP-1 adaptor complex (biogroup)


Body Atlas

Most Correlated Tissues

  1. Synovial membrane
  2. Heart atrium
  3. Omental adipose tissue
  4. Heart
  5. Joint synovium
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Disease Atlas

Most Correlated Diseases

  1. Bacterial septicemia
  2. Hypercholesterolemia
  3. Whipple's disease
  4. Septicemia due to Klebsiella
  5. Disease due to Orthopoxvirus
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Pharmaco Atlas

Most Correlated Compounds

  1. ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide)
  2. SN-38
  3. CGP 60474
  4. niguldipine
  5. A 443654
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. LZIC
  2. CCDC170
  3. DDX25
  4. ACAA1
  5. NAPEPLD
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Neuronal NEU cells treated with small molecule perturbagens
  2. L1000 CMAP - Neural progenitor NPC.CAS9 cells treated with small molecule perturbagens
  3. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
  4. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
  5. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
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Literature

Most Relevant Literature

  1. Involvement of the AP-1 adaptor complex in early steps of phagocytosis and macropinocytosis.
  2. Nef-induced alteration of the early/recycling endosomal compartment correlates with enhancement of H…
  3. A dileucine motif and a cluster of acidic amino acids in the second cytoplasmic domain of the batten…
  4. Regions of human kidney anion exchanger 1 (kAE1) required for basolateral targeting of kAE1 in polar…
  5. Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with c…
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Clinical Trials

Most Relevant Clinical Trials

  1. Melpida: Recombinant Adeno-associated Virus (Serotype 9) Encoding a Codon Optimized Human AP4M1 Tran…
  2. Plasmodium Falciparum Genomic Intelligence in Mozambique
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