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To investigate the alkaloids from the stem of Artabotrys hainanensis. Compounds in plant extracts were separated by silica gel and sephadex LH-20 column chromatography. Chemical structures were elucidated by chemical and spectral analyses including UV, 1H-NMR, 13C-NMR, ESIMS and ESI-MS-MS. Eight alkaloids were isolated and identified as spinosine (1), 3-hydroxynornuciferine (2), juzirine (3), artabotrine (4), liridine (5), assimilobine (6), isococlaurine (7), N-demethylarmepavine (8). All alkaloids were isolated from this plant for the first time and compounds 1, 3, 7 and 8 were isolated from genus Artabotrys for the first time.


Chang-ri Han, Guo-yuan Zhu, Guang-ying Chen, Han-yang Zhang, He-ping Bi, Hong-xun Fang. Studies on the alkaloids from stem of Artabotrys hainanensis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2005 Nov;30(21):1660-2

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PMID: 16400942

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