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QuickView for isoquinolines (compound)


Genetic Markers

Most Correlated Genes

  1. ATF3
  2. PDE4B
  3. CYP1A1
  4. FOS
  5. EGR1
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Pathway Enrichment

Most Correlated Biogroups

  1. regulation of nitrogen compound metabolic process
  2. heterocyclic compound binding
  3. organic cyclic compound binding
  4. organic cyclic compound metabolic process
  5. heterocycle metabolic process
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Curated Studies

Most Correlated Studies

  1. Genomics Assisted Toxicity Evaluation system study - Human Hepatocytes
  2. Genomics Assisted Toxicity Evaluation system study - Rat Liver Single Dose
  3. Genomics Assisted Toxicity Evaluation system study - Rat Liver Repeat Doses
  4. Genomics Assisted Toxicity Evaluation system study - Rat Hepatocytes
  5. Drug Matrix In Vivo Toxicogenomic Study - Rat Spleen [Codelink]
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Literature

Most Relevant Literature

  1. 5,6-Dihydropyrrolo[2,1-a]isoquinolines as Alternative of New Drugs with Cytotoxic Activity.
  2. A divergent approach to benzylisoquinoline-type and oxoaporphine alkaloids via regioselective direct…
  3. An efficient synthesis of isoquinolines via rhodium-catalyzed direct C-H functionalization of arylhy…
  4. 1-Trifluoromethylated isoquinolines via radical trifluoromethylation of isonitriles.
  5. Modelling antibiotic and cytotoxic isoquinoline effects in Staphylococcus aureus, Staphylococcus epi…
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Clinical Trials

Most Relevant Clinical Trials

  1. Assessing Goldenseal-drug Interactions Using a Probe Drug Cocktail Approach
  2. Comparison of Berberine and Metformin for the Treatment for MS in Schizophrenia Patients
  3. Primary Chemoprevention of Familial Adenomatous Polyposis With Berberine Hydrochloride
  4. PET Imaging of Brain Peripheral Benzodiazepine Receptors
  5. Combination of Danazole With Berberine in the Treatment of ITP
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