Comparative evaluation of Tc-99m cystine and Tc-99m MAG3 in normals and patients with renal functional impairment.

Mridula Misra, Prasanta K Pradhan, Kakali De, Susmita Chandra, Birendra K Das

Nuclear Medicine Division, Indian Institute of Chemical Biology, Kolkata, West Bengal, India. mridulamisra@iicb.res.in

Clinical nuclear medicine 2009 Mar

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Tc-99m cystine has been proved to be a good renal agent in animals for morphologic as well as the functional status of the kidney. In this study, we compared Tc-99m cystine with Tc-99m mercaptoacetyltriglycine, which is used for evaluation of renal function in normal patients, and those with various degrees of renal functional impairment. The clearance values and static images are compared with Tc-99m mercaptoacetyltriglycine. The results show that Tc-99m cystine has good radiopharmaceutical characteristics suitable for evaluation of both renal function as well as morphology.

Citation

Mridula Misra, Prasanta K Pradhan, Kakali De, Susmita Chandra, Birendra K Das. Comparative evaluation of Tc-99m cystine and Tc-99m MAG3 in normals and patients with renal functional impairment. Clinical nuclear medicine. 2009 Mar;34(3):141-5