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renal impairment
(phenotype)
Summary
General Info
Genetic Markers
Most Correlated Genes
Most Correlated SNPs
CD46
CFH
EGR1
C3
C1GALT1C1
No SNPs found
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Pathway Enrichment
Most Correlated Biogroups
immune response
REACTOME_IMMUNE_SYSTEM
response to stress
regulation of immune response
vesicle
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Curated Studies
Most Correlated Studies
Whole blood expression profiles of uremic patients
CD4+ T cells from an atypical hemolytic uremic syndrome (aHUS) patient carrying mutant CD46
Whole blood from end stage renal disease patients before and after nocturnal hemodialysis treatment
Kidneys with AKI and Drosha knockdown - mesenchymal stromal cells or extracellular vesicles treated
CD8+ T cells from blood of CD46-deficient patients activated with antibodies against CD3 and CD46
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Literature
Most Relevant Literature
Renin-Angiotensin-Aldosterone System Inhibitions and Cardiovascular Outcomes in Acute Myocardial Inf…
Renal impairment and mortality in patients with STEMI and cardiogenic shock/cardiac arrest.
Teclistamab in patients with multiple myeloma and impaired renal function.
Impact of renal impairment on dihydropyrimidine dehydrogenase (DPD) phenotyping.
Low-dose apatinib in subjects with renal impairment: A pharmacokinetics study.
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Clinical Trials
Most Relevant Clinical Trials
Pharmacokinetics in Subjects With Renal Impairment
Fruquintinib Renal Impairment Study
Surufatinib Renal Impairment Study
Lorlatinib Renal Impairment Study
Safinamide Renal Impairment Trial
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