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An efficient route to 1-aminoisoquinolines via AgOTf-catalyzed reaction of 2-alkynylbenzaldoxime with amine.
Danqing Zheng, Zhiyuan Chen, Jianping Liu, Jie Wu
Department of Chemistry, Fudan University, 220 Handan Road, Shanghai, 200433, China.
Organic & biomolecular chemistry 2011 Jul 7Sizes of these terms reflect their relevance to your search.
2-Alkynylbenzaldoxime reacts with amine catalyzed by silver triflate under mild conditions, leading to 1-aminoisoquinolines in good yield. This reaction proceeds efficiently with good functional group tolerance.
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Danqing Zheng, Zhiyuan Chen, Jianping Liu, Jie Wu. An efficient route to 1-aminoisoquinolines via AgOTf-catalyzed reaction of 2-alkynylbenzaldoxime with amine. Organic & biomolecular chemistry. 2011 Jul 7;9(13):4763-5
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PMID: 21617812
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