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RhCp*Cl(2)](2) can catalyze the oxidative coupling of N-aryl and N-alkyl benzamidines with alkynes to give N-substituted 1-aminoisoquinolines in high selectivity.

Citation

Xiaohong Wei, Miao Zhao, Zhengyin Du, Xingwei Li. Synthesis of 1-aminoisoquinolines via Rh(III)-catalyzed oxidative coupling. Organic letters. 2011 Sep 2;13(17):4636-9

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PMID: 21812407

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