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The exact etiology and pathogenesis of knee osteoarthritis (KOA) are still unknown and it is hard to treat the disease fundamentally. With new therapeutic methods and techniques appearing, the present situation of treating the disease will be changed in the near future. Basic research of knee osteoarthritis will contribute to clarifying the pathogenesis and exploring the therapeutic methods. This article makes a brief review on the up-to-date basic researches of knee osteoarthritis by reviewing literature concerned in recent years.


Yun Zhai, Gen-De Gao, Shou-Yu Xu. Basic research progress of knee osteoarthritis]. Zhongguo gu shang = China journal of orthopaedics and traumatology. 2012 Jan;25(1):83-7

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PMID: 22489534

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