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Neurodegeneration with brain iron accumulation is a group of disorders, the commonest of which is PKAN (Pantothenate kinase associated neurodegeneration). We present here, a case of 18 year old boy with progressive dementia, pyramidal and extrapyramidal involvement, dysarthria, seizures and myoclonus. The patient was diagnosed as PKAN (formerly Hallervorden Spatz disease) after "eye of tiger" appearance on neuro-imaging.


Alpana Parmar, Shruti Khare, Vipul Srivastav. Pantothenate - kinase associated neurodegeneration. The Journal of the Association of Physicians of India. 2012 Apr;60:74-6

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PMID: 23029753

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