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In this issue, Trinidad et al. (2013) show that CCT/TRiC is a chaperone required for p53 folding, thus providing another layer of regulation of p53 function, with implications for cancer therapeutics targeting the p53 pathway. Copyright © 2013 Elsevier Inc. All rights reserved.


Jessica Monteith, Steven B McMahon. p53: the TRiC is knowing when to fold 'em. Molecular cell. 2013 Jun 27;50(6):781-2

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PMID: 23806333

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