Components of the complement system act directly on T cells to alter conventional and regulatory T cell subsets. In this issue of Immunity, Kolev, Dimeloe, Le Friec et al. (2015) provide evidence of a mechanism by which the complement stimulates sustained mTORC1 activation and regulates cellular metabolism. Copyright © 2015 Elsevier Inc. All rights reserved.
Mark R Boothby, Ariel L Raybuck, Sung Hoon Cho. Complementing T Cells' Functions: Bringing in Metabolism Matters. Immunity. 2015 Jun 16;42(6):977-9
PMID: 26084014
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