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Experiments on small (rats) and large (dogs) animals have shown that a sequential administration of Palonosetron and Phenotropil decreases the intensity of the main manifestations of the N-V-D stage of acute radiation syndrome. These data show the appropriateness of a combined administration of Palonosetron and Phenotropil to prevent a reduced work capacity in the individuals participating in elimination of the consequences of accidents associated with overexposure to radiation.


I S Drachouv, V N Bykov, A B Seleznev. Administration of Palonosetron and Phenotropil for Prophylaxis of the N-V-D Stage of Acute Radiation Syndrome]. Radiatsionnaia biologiia, radioecologiia / Rossiĭskaia akademiia nauk. 2016 Jan-Feb;56(1):64-72

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PMID: 27245006

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